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Shaping the regulation of the p53 mRNA tumour suppressor: the co-evolution of genetic signatures

Structured RNA regulatory motifs exist from the prebiotic stages of the RNA world to the more complex eukaryotic systems. In cases where a functional RNA structure is within the coding sequence a selective pressure drives a parallel co-evolution of the RNA structure and the encoded peptide domain. T...

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Detalles Bibliográficos
Autores principales: Karakostis, Konstantinos, Fåhraeus, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743176/
https://www.ncbi.nlm.nih.gov/pubmed/31519161
http://dx.doi.org/10.1186/s12885-019-6118-y