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Shaping the regulation of the p53 mRNA tumour suppressor: the co-evolution of genetic signatures
Structured RNA regulatory motifs exist from the prebiotic stages of the RNA world to the more complex eukaryotic systems. In cases where a functional RNA structure is within the coding sequence a selective pressure drives a parallel co-evolution of the RNA structure and the encoded peptide domain. T...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743176/ https://www.ncbi.nlm.nih.gov/pubmed/31519161 http://dx.doi.org/10.1186/s12885-019-6118-y |