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Longitudinal variation in human immunodeficiency virus long terminal repeat methylation in individuals on suppressive antiretroviral therapy

BACKGROUND: Persistence of latent, replication-competent provirus in CD4(+) T cells of human immunodeficiency virus (HIV)-infected individuals on antiretroviral treatment (ART) is the main obstacle for virus eradication. Methylation of the proviral 5′ long terminal repeat (LTR) promoter region has b...

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Detalles Bibliográficos
Autores principales: Cortés-Rubio, César N., Salgado-Montes de Oca, Gonzalo, Prado-Galbarro, Francisco J., Matías-Florentino, Margarita, Murakami-Ogasawara, Akio, Kuri-Cervantes, Leticia, Carranco-Arenas, Ana P., Ormsby, Christopher E., Cortés-Rubio, Ivette K., Reyes-Terán, Gustavo, Ávila-Ríos, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743183/
https://www.ncbi.nlm.nih.gov/pubmed/31519219
http://dx.doi.org/10.1186/s13148-019-0735-9