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Mitochondrial dysregulation and muscle disuse atrophy

It is well established that mitochondria play a critical role in the metabolic and physiological adaptation of skeletal muscle to enhanced contractile activity. Several redox-sensitive signaling pathways such as PGC-1α, AMPK, IGF/Akt/mTOR, SIRT, NFκB, and FoxO are involved with extensive crosstalk t...

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Detalles Bibliográficos
Autores principales: Ji, Li Li, Yeo, Dongwook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743252/
https://www.ncbi.nlm.nih.gov/pubmed/31559011
http://dx.doi.org/10.12688/f1000research.19139.1