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Deletion of CD163 Exon 7 Confers Resistance to Highly Pathogenic Porcine Reproductive and Respiratory Viruses on Pigs

Porcine reproductive and respiratory syndrome (PRRS) caused by PRRS virus (PRRSV) is a severe infectious disease in the swine industry. PRRSV infection is mediated by porcine CD163 (pCD163). Scavenger receptor cysteine-rich domain 5 coded by exon 7 of pCD163 is essential for PRRSV infection. In this...

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Detalles Bibliográficos
Autores principales: Wang, Haitao, Shen, Liangcai, Chen, Jingyao, Liu, Xiaojuan, Tan, Tan, Hu, Yiqing, Bai, Xiaofei, Li, Yuexin, Tian, Kegong, Li, Ning, Hu, Xiaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743298/
https://www.ncbi.nlm.nih.gov/pubmed/31523199
http://dx.doi.org/10.7150/ijbs.34269