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Emerging Epigenetic Therapeutic Targets in Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a genetically heterogeneous malignancy for which treatment options have been largely limited to cytotoxic chemotherapy for the past four decades. Next-generation sequencing and other approaches have identified a spectrum of genomic and epigenomic alterations that cont...

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Detalles Bibliográficos
Autores principales: Wingelhofer, Bettina, Somervaille, Tim C. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743337/
https://www.ncbi.nlm.nih.gov/pubmed/31552175
http://dx.doi.org/10.3389/fonc.2019.00850