SNX8 Enhances Non-amyloidogenic APP Trafficking and Attenuates Aβ Accumulation and Memory Deficits in an AD Mouse

Dysregulation of various APP trafficking components in the endosome has been previously implicated in Alzheimer’s disease (AD). Although single nucleotide polymorphisms within the gene locus encoding the endosomal component, SNX8 have been previously associated with AD, how SNX8 levels are altered a...

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Detalles Bibliográficos
Autores principales: Xie, Yongzhuang, Niu, Mengxi, Ji, Chengxiang, Huang, Timothy Y., Zhang, Cuilin, Tian, Ye, Shi, Zhun, Wang, Chen, Zhao, Yingjun, Luo, Hong, Can, Dan, Xu, Huaxi, Zhang, Yun-wu, Zhang, Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743354/
https://www.ncbi.nlm.nih.gov/pubmed/31551717
http://dx.doi.org/10.3389/fncel.2019.00410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743354/
https://www.ncbi.nlm.nih.gov/pubmed/31551717
http://dx.doi.org/10.3389/fncel.2019.00410

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