Phenolic acid phenethylesters and their corresponding ketones: Inhibition of 5‐lipoxygenase and stability in human blood and HepaRG cells

5‐lipoxygenase (5‐LO) catalyzes the biosynthesis of leukotrienes, potent lipid mediators involved in inflammatory diseases, and both 5‐LO and the leukotrienes are validated therapeutic targets. Caffeic acid phenethyl ester (CAPE) is an effective inhibitor of 5‐LO and leukotriene biosynthesis but is...

Descripción completa

Detalles Bibliográficos
Autores principales: Mbarik, Maroua, Poirier, Samuel J., Doiron, Jérémie, Selka, Ayyoub, Barnett, David A., Cormier, Marc, Touaibia, Mohamed, Surette, Marc E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743424/
https://www.ncbi.nlm.nih.gov/pubmed/31523435
http://dx.doi.org/10.1002/prp2.524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743424/
https://www.ncbi.nlm.nih.gov/pubmed/31523435
http://dx.doi.org/10.1002/prp2.524

Ejemplares similares