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Physicochemical mechanotransduction alters nuclear shape and mechanics via heterochromatin formation
The nucleus houses, organizes, and protects chromatin to ensure genome integrity and proper gene expression, but how the nucleus adapts mechanically to changes in the extracellular environment is poorly understood. Recent studies have revealed that extracellular physical stresses induce chromatin co...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743459/ https://www.ncbi.nlm.nih.gov/pubmed/31365328 http://dx.doi.org/10.1091/mbc.E19-05-0286 |