Physicochemical mechanotransduction alters nuclear shape and mechanics via heterochromatin formation

The nucleus houses, organizes, and protects chromatin to ensure genome integrity and proper gene expression, but how the nucleus adapts mechanically to changes in the extracellular environment is poorly understood. Recent studies have revealed that extracellular physical stresses induce chromatin co...

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Detalles Bibliográficos
Autores principales: Stephens, Andrew D., Liu, Patrick Z., Kandula, Viswajit, Chen, Haimei, Almassalha, Luay M., Herman, Cameron, Backman, Vadim, O’Halloran, Thomas, Adam, Stephen A., Goldman, Robert D., Banigan, Edward J., Marko, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743459/
https://www.ncbi.nlm.nih.gov/pubmed/31365328
http://dx.doi.org/10.1091/mbc.E19-05-0286

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