An actin-based protrusion originating from a podosome-enriched region initiates macrophage fusion

Macrophage fusion resulting in the formation of multinucleated giant cells occurs in a variety of chronic inflammatory diseases, yet the mechanism responsible for initiating this process is unknown. Here, we used live cell imaging to show that actin-based protrusions at the leading edge initiate mac...

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Detalles Bibliográficos
Autores principales: Faust, James J., Balabiyev, Arnat, Heddleston, John M., Podolnikova, Nataly P., Baluch, D. Page, Chew, Teng-Leong, Ugarova, Tatiana P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743464/
https://www.ncbi.nlm.nih.gov/pubmed/31242090
http://dx.doi.org/10.1091/mbc.E19-01-0009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743464/
https://www.ncbi.nlm.nih.gov/pubmed/31242090
http://dx.doi.org/10.1091/mbc.E19-01-0009

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