Targeting EZH1/2 induces cell cycle arrest and inhibits cell proliferation through reactivation of p57(CDKN1C) and TP53INP1 in mantle cell lymphoma

OBJECTIVE: To explore the effect of dysregulation of epigenetic regulator EZH1 and EZH2 on the proliferation in MCL and the underlying mechanisms. METHODS: In this study, we elucidated the role of EZH1 and EZH2 overexpression by immunohistochemistry and correlated them to clinical outcome in 41 MCL...

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Detalles Bibliográficos
Autores principales: Li, Wei, Bi, Chengfeng, Han, Yating, Tian, Tian, Wang, Xianhuo, Bao, Huijing, Xu, Xiaoying, Zhang, Xuhan, Liu, Lu, Zhang, Weiwei, Gao, Hai, Wang, Huaqing, Zhang, Huilai, Meng, Bin, Wang, Xi, Fu, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743615/
https://www.ncbi.nlm.nih.gov/pubmed/31565482
http://dx.doi.org/10.20892/j.issn.2095-3941.2018.0380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743615/
https://www.ncbi.nlm.nih.gov/pubmed/31565482
http://dx.doi.org/10.20892/j.issn.2095-3941.2018.0380

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