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Prevalence and clinical significance of pathogenic germline BRCA1/2 mutations in Chinese non-small cell lung cancer patients

OBJECTIVE: Germline alterations in the breast cancer susceptibility genes type 1 and 2, BRCA1 and BRCA2, predispose individuals to hereditary cancers, including breast, ovarian, prostate, pancreatic, and stomach cancers. Accumulating evidence suggests inherited genetic susceptibility to lung cancer....

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Detalles Bibliográficos
Autores principales: Hu, Xingsheng, Yang, Dongyong, Li, Yalun, Li, Li, Wang, Yan, Chen, Peng, Xu, Song, Pu, Xingxiang, Zhu, Wei, Deng, Pengbo, Ye, Junyi, Zhang, Hanhan, Lizaso, Analyn, Liu, Hao, Mao, Xinru, Huang, Hai, Chu, Qian, Hu, Chengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743617/
https://www.ncbi.nlm.nih.gov/pubmed/31565484
http://dx.doi.org/10.20892/j.issn.2095-3941.2018.0506