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CSN6 promotes tumorigenesis of gastric cancer by ubiquitin-independent proteasomal degradation of p16(INK4a)

OBJECTIVE: CSN6 is a vital subunit of the constitutive photomorphogenesis 9 (COP9) signalosome (CSN), which is responsible for development disorders and promotes ubiquitin-26S proteasome-dependent degradation in vitro and vivo. Its role in the tumor development of gastric cancer remains unclear. In...

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Detalles Bibliográficos
Autores principales: Du, Wenqi, Liu, Zongxiang, Zhu, Wentao, Li, Tongtong, Zhu, Zhiman, Wei, Lulu, Song, Jun, Pei, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743625/
https://www.ncbi.nlm.nih.gov/pubmed/31565481
http://dx.doi.org/10.20892/j.issn.2095-3941.2018.0410