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Voltage gated sodium channels as therapeutic targets for chronic pain

Being maladaptive and frequently unresponsive to pharmacotherapy, chronic pain presents a major unmet clinical need. While an intact central nervous system is required for conscious pain perception, nociceptor hyperexcitability induced by nerve injury in the peripheral nervous system (PNS) is suffic...

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Detalles Bibliográficos
Autores principales: Ma, Renee Siu Yu, Kayani, Kayani, Whyte-Oshodi, Danniella, Whyte-Oshodi, Aiyesha, Nachiappan, Nitish, Gnanarajah, Shaene, Mohammed, Raihan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743634/
https://www.ncbi.nlm.nih.gov/pubmed/31564962
http://dx.doi.org/10.2147/JPR.S207610