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Benchmarking network propagation methods for disease gene identification

In-silico identification of potential target genes for disease is an essential aspect of drug target discovery. Recent studies suggest that successful targets can be found through by leveraging genetic, genomic and protein interaction information. Here, we systematically tested the ability of 12 var...

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Detalles Bibliográficos
Autores principales: Picart-Armada, Sergio, Barrett, Steven J., Willé, David R., Perera-Lluna, Alexandre, Gutteridge, Alex, Dessailly, Benoit H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743778/
https://www.ncbi.nlm.nih.gov/pubmed/31479437
http://dx.doi.org/10.1371/journal.pcbi.1007276