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Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity

WW domain tandem-containing proteins such as KIBRA, YAP, and MAGI play critical roles in cell growth and polarity via binding to and positioning target proteins in specific subcellular regions. An immense disparity exists between promiscuity of WW domain-mediated target bindings and specific roles o...

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Detalles Bibliográficos
Autores principales: Lin, Zhijie, Yang, Zhou, Xie, Ruiling, Ji, Zeyang, Guan, Kunliang, Zhang, Mingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744271/
https://www.ncbi.nlm.nih.gov/pubmed/31486770
http://dx.doi.org/10.7554/eLife.49439