Cargando…

High-resolution and high-accuracy topographic and transcriptional maps of the nucleosome barrier

Nucleosomes represent mechanical and energetic barriers that RNA Polymerase II (Pol II) must overcome during transcription. A high-resolution description of the barrier topography, its modulation by epigenetic modifications, and their effects on Pol II nucleosome crossing dynamics, is still missing....

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Zhijie, Gabizon, Ronen, Brown, Aidan I, Lee, Antony, Song, Aixin, Díaz-Celis, César, Kaplan, Craig D, Koslover, Elena F, Yao, Tingting, Bustamante, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744274/
https://www.ncbi.nlm.nih.gov/pubmed/31364986
http://dx.doi.org/10.7554/eLife.48281