Comparative fitness analysis of D-cycloserine resistant mutants reveals both fitness-neutral and high-fitness cost genotypes

Drug resistant infections represent one of the most challenging medical problems of our time. D-cycloserine is an antibiotic used for six decades without significant appearance and dissemination of antibiotic resistant strains, making it an ideal model compound to understand what drives resistance e...

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Detalles Bibliográficos
Autores principales: Evangelopoulos, Dimitrios, Prosser, Gareth A., Rodgers, Angela, Dagg, Belinda M., Khatri, Bhagwati, Ho, Mei Mei, Gutierrez, Maximiliano G., Cortes, Teresa, de Carvalho, Luiz Pedro S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744398/
https://www.ncbi.nlm.nih.gov/pubmed/31519879
http://dx.doi.org/10.1038/s41467-019-12074-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744398/
https://www.ncbi.nlm.nih.gov/pubmed/31519879
http://dx.doi.org/10.1038/s41467-019-12074-z

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