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Use of a Lymphatic Drug Delivery System and Sonoporation to Target Malignant Metastatic Breast Cancer Cells Proliferating in the Marginal Sinuses

Lymph node (LN) metastasis through the lymphatic network is a major route for cancer dissemination. Tumor cells reach the marginal sinuses of LNs via afferent lymphatic vessels (LVs) and form metastatic lesions that lead to distant metastasis. Thus, targeting of metastatic cells in the marginal sinu...

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Detalles Bibliográficos
Autores principales: Kato, Shigeki, Shirai, Yuko, Sakamoto, Maya, Mori, Shiro, Kodama, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744402/
https://www.ncbi.nlm.nih.gov/pubmed/31519920
http://dx.doi.org/10.1038/s41598-019-49386-5