Infection with mosquito-borne alphavirus induces selective loss of dopaminergic neurons, neuroinflammation and widespread protein aggregation

Neuroinvasive infections with mosquito-borne alphaviruses such as Western equine encephalitis virus (WEEV) can cause post-encephalitic parkinsonism. To understand the mechanisms underlying these neurological effects, we examined the capacity of WEEV to induce progressive neurodegeneration in outbred...

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Detalles Bibliográficos
Autores principales: Bantle, Collin M., Phillips, Aaron T., Smeyne, Richard J., Rocha, Savannah M., Olson, Ken E., Tjalkens, Ronald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744428/
https://www.ncbi.nlm.nih.gov/pubmed/31531390
http://dx.doi.org/10.1038/s41531-019-0090-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744428/
https://www.ncbi.nlm.nih.gov/pubmed/31531390
http://dx.doi.org/10.1038/s41531-019-0090-8

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