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Infection with mosquito-borne alphavirus induces selective loss of dopaminergic neurons, neuroinflammation and widespread protein aggregation
Neuroinvasive infections with mosquito-borne alphaviruses such as Western equine encephalitis virus (WEEV) can cause post-encephalitic parkinsonism. To understand the mechanisms underlying these neurological effects, we examined the capacity of WEEV to induce progressive neurodegeneration in outbred...
Autores principales: | Bantle, Collin M., Phillips, Aaron T., Smeyne, Richard J., Rocha, Savannah M., Olson, Ken E., Tjalkens, Ronald B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744428/ https://www.ncbi.nlm.nih.gov/pubmed/31531390 http://dx.doi.org/10.1038/s41531-019-0090-8 |
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