UPF1/SMG7-dependent microRNA-mediated gene regulation

The stability and quality of metazoan mRNAs are under microRNA (miRNA)-mediated and nonsense-mediated control. Although UPF1, a core mediator of nonsense-mediated mRNA decay (NMD), mediates the decay of target mRNA in a 3′UTR-length-dependent manner, the detailed mechanism remains unclear. Here, we...

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Detalles Bibliográficos
Autores principales: Park, Jungyun, Seo, Jwa-Won, Ahn, Narae, Park, Seokju, Hwang, Jungwook, Nam, Jin-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744440/
https://www.ncbi.nlm.nih.gov/pubmed/31519907
http://dx.doi.org/10.1038/s41467-019-12123-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744440/
https://www.ncbi.nlm.nih.gov/pubmed/31519907
http://dx.doi.org/10.1038/s41467-019-12123-7

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