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The Plasma Interleukin (IL)-35 Level and Frequency of Circulating IL-35(+) Regulatory B Cells are Decreased in a Cohort of Chinese Patients with New-onset Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease that is associated with the destruction of immune tolerance and activation of B cells. Interleukin (IL)-35 and IL-35-producing (IL-35(+)) regulatory B cells (Bregs) have been demonstrated to possess immunosuppressive functions,...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744462/ https://www.ncbi.nlm.nih.gov/pubmed/31519970 http://dx.doi.org/10.1038/s41598-019-49748-z |