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The Plasma Interleukin (IL)-35 Level and Frequency of Circulating IL-35(+) Regulatory B Cells are Decreased in a Cohort of Chinese Patients with New-onset Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease that is associated with the destruction of immune tolerance and activation of B cells. Interleukin (IL)-35 and IL-35-producing (IL-35(+)) regulatory B cells (Bregs) have been demonstrated to possess immunosuppressive functions,...

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Detalles Bibliográficos
Autores principales: Ye, Zhuang, Jiang, Yanfang, Sun, Dejun, Zhong, Wei, Zhao, Ling, Jiang, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744462/
https://www.ncbi.nlm.nih.gov/pubmed/31519970
http://dx.doi.org/10.1038/s41598-019-49748-z