Development of R7BP inhibitors through cross-linking coupled mass spectrometry and integrated modeling

Protein-protein interaction (PPI) networks are known to be valuable targets for therapeutic intervention; yet the development of PPI modulators as next-generation drugs to target specific vertices, edges, and hubs has been impeded by the lack of structural information of many of the proteins and com...

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Detalles Bibliográficos
Autores principales: Adikaram, Poorni R., Zhang, Jian-Hua, Kittock, Claire M., Pandey, Mritunjay, Hassan, Sergio A., Lue, Nicole G., Wang, Guanghui, Gucek, Marjan, Simonds, William F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744478/
https://www.ncbi.nlm.nih.gov/pubmed/31531399
http://dx.doi.org/10.1038/s42003-019-0585-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744478/
https://www.ncbi.nlm.nih.gov/pubmed/31531399
http://dx.doi.org/10.1038/s42003-019-0585-1

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