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Development of R7BP inhibitors through cross-linking coupled mass spectrometry and integrated modeling
Protein-protein interaction (PPI) networks are known to be valuable targets for therapeutic intervention; yet the development of PPI modulators as next-generation drugs to target specific vertices, edges, and hubs has been impeded by the lack of structural information of many of the proteins and com...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744478/ https://www.ncbi.nlm.nih.gov/pubmed/31531399 http://dx.doi.org/10.1038/s42003-019-0585-1 |