Tumour-specific Causal Inference Discovers Distinct Disease Mechanisms Underlying Cancer Subtypes

Cancer is a disease mainly caused by somatic genome alterations (SGAs) that perturb cellular signalling systems. Furthermore, the combination of pathway aberrations in a tumour defines its disease mechanism, and distinct disease mechanisms underlie the inter-tumour heterogeneity in terms of disease...

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Detalles Bibliográficos
Autores principales: Xue, Yifan, Cooper, Gregory, Cai, Chunhui, Lu, Songjian, Hu, Baoli, Ma, Xiaojun, Lu, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744493/
https://www.ncbi.nlm.nih.gov/pubmed/31519988
http://dx.doi.org/10.1038/s41598-019-48318-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744493/
https://www.ncbi.nlm.nih.gov/pubmed/31519988
http://dx.doi.org/10.1038/s41598-019-48318-7

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