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Tumour-specific Causal Inference Discovers Distinct Disease Mechanisms Underlying Cancer Subtypes

Cancer is a disease mainly caused by somatic genome alterations (SGAs) that perturb cellular signalling systems. Furthermore, the combination of pathway aberrations in a tumour defines its disease mechanism, and distinct disease mechanisms underlie the inter-tumour heterogeneity in terms of disease...

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Detalles Bibliográficos
Autores principales:	Xue, Yifan, Cooper, Gregory, Cai, Chunhui, Lu, Songjian, Hu, Baoli, Ma, Xiaojun, Lu, Xinghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744493/ https://www.ncbi.nlm.nih.gov/pubmed/31519988 http://dx.doi.org/10.1038/s41598-019-48318-7

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