Phylogenetic and functional characterisation of the Haemophilus influenzae multidrug efflux pump AcrB

Multidrug resistance in Gram-negative bacteria can arise by the over-expression of multidrug efflux pumps, which can extrude a wide range of antibiotics. Here we describe the ancestral Haemophilus influenzae efflux pump AcrB (AcrB-Hi). We performed a phylogenetic analysis of hundreds of RND-type tra...

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Detalles Bibliográficos
Autores principales: Zwama, Martijn, Yamaguchi, Akihito, Nishino, Kunihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744504/
https://www.ncbi.nlm.nih.gov/pubmed/31531401
http://dx.doi.org/10.1038/s42003-019-0564-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744504/
https://www.ncbi.nlm.nih.gov/pubmed/31531401
http://dx.doi.org/10.1038/s42003-019-0564-6

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