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Synergistically Enhanced Inhibitory Effects of Pullulan Nanoparticle-Mediated Co-Delivery of Lovastatin and Doxorubicin to Triple-Negative Breast Cancer Cells

Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is prone to drug resistance and difficult to treat. In this study, we grafted water-soluble pullulan with lovastatin (LV) to develop a novel amphiphilic conjugate, pullulan-encapsulated LV (PLV). The PLV conjugate was synthesize...

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Detalles Bibliográficos
Autores principales: Wu, Di, Chen, Yao, Wen, Shun, Wen, Yi, Wang, Rong, Zhang, Qiuting, Qin, Ge, Yi, Huimei, Wu, Mi, Lu, Lu, Tao, Xiaojun, Deng, Xiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744545/
https://www.ncbi.nlm.nih.gov/pubmed/31520223
http://dx.doi.org/10.1186/s11671-019-3146-0