Fatty acid transport protein 4 is required for incorporation of saturated ultralong-chain fatty acids into epidermal ceramides and monoacylglycerols

Fatty acid transport protein 4 (FATP4) is an acyl-CoA synthetase that is required for normal permeability barrier in mammalian skin. FATP4 (SLC27A4) mutations cause ichthyosis prematurity syndrome, a nonlethal disorder. In contrast, Fatp4(−/−) mice die neonatally from a defective barrier. Here we us...

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Detalles Bibliográficos
Autores principales: Lin, Meei-Hua, Hsu, Fong-Fu, Crumrine, Debra, Meyer, Jason, Elias, Peter M., Miner, Jeffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744566/
https://www.ncbi.nlm.nih.gov/pubmed/31519952
http://dx.doi.org/10.1038/s41598-019-49684-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744566/
https://www.ncbi.nlm.nih.gov/pubmed/31519952
http://dx.doi.org/10.1038/s41598-019-49684-y

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