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Energetic costs regulated by cell mechanics and confinement are predictive of migration path during decision-making
Cell migration during the invasion-metastasis cascade requires cancer cells to navigate a spatially complex microenvironment that presents directional choices to migrating cells. Here, we investigate cellular energetics during migration decision-making in confined spaces. Theoretical and experimenta...
Autores principales: | Zanotelli, Matthew R., Rahman-Zaman, Aniqua, VanderBurgh, Jacob A., Taufalele, Paul V., Jain, Aadhar, Erickson, David, Bordeleau, Francois, Reinhart-King, Cynthia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744572/ https://www.ncbi.nlm.nih.gov/pubmed/31519914 http://dx.doi.org/10.1038/s41467-019-12155-z |
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