RhoBTB1 interacts with ROCKs and inhibits invasion

RhoBTB1 is an atypical Rho GTPase with two BTB domains in addition to its Rho domain. Although most Rho GTPases regulate actin cytoskeletal dynamics, RhoBTB1 is not known to affect cell shape or motility. We report that RhoBTB1 depletion increases prostate cancer cell invasion and induces elongation...

Descripción completa

Detalles Bibliográficos
Autores principales: Haga, Raquel B., Garg, Ritu, Collu, Francesca, Borda D'Agua, Bárbara, Menéndez, Sofia T., Colomba, Audrey, Fraternali, Franca, Ridley, Anne J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744581/
https://www.ncbi.nlm.nih.gov/pubmed/31431478
http://dx.doi.org/10.1042/BCJ20190203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744581/
https://www.ncbi.nlm.nih.gov/pubmed/31431478
http://dx.doi.org/10.1042/BCJ20190203

Ejemplares similares