Dose-adjusted and dose/kg-adjusted concentrations of mycophenolic acid precursors reflect metabolic ratios of their metabolites in contrast with tacrolimus and cyclosporine

Background and purpose: Therapeutic drug monitoring is a valuable tool supporting immunosuppressive therapy. Significant variation of immunosuppressive drug (ISD) concentrations during their use at similar doses is the basis of dose-normalization strategy. The strategy of dose-adjustment is proposed...

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Detalles Bibliográficos
Autores principales: Hryniewiecka, Ewa, Żegarska, Jolanta, Żochowska, Dorota, Samborowska, Emilia, Jaźwiec, Radosław, Kosieradzki, Maciej, Nazarewski, Sławomir, Dadlez, Michał, Pączek, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744583/
https://www.ncbi.nlm.nih.gov/pubmed/31395739
http://dx.doi.org/10.1042/BSR20182031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744583/
https://www.ncbi.nlm.nih.gov/pubmed/31395739
http://dx.doi.org/10.1042/BSR20182031

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