Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia

BACKGROUND: Preeclampsia is a pregnancy-specific hypertensive disorder characterized by impaired angiogenesis. We postulate that senescence of mesenchymal stem cells (MSC), multipotent cells with pro-angiogenic activities, is one of the mechanisms by which systemic inflammation exerts inhibitory eff...

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Detalles Bibliográficos
Autores principales: Suvakov, Sonja, Cubro, Hajrunisa, White, Wendy M., Butler Tobah, Yvonne S., Weissgerber, Tracey L., Jordan, Kyra L., Zhu, Xiang Y., Woollard, John R., Chebib, Fouad T., Milic, Natasa M., Grande, Joseph P., Xu, Ming, Tchkonia, Tamara, Kirkland, James L., Lerman, Lilach O., Garovic, Vesna D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744626/
https://www.ncbi.nlm.nih.gov/pubmed/31521202
http://dx.doi.org/10.1186/s13293-019-0263-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744626/
https://www.ncbi.nlm.nih.gov/pubmed/31521202
http://dx.doi.org/10.1186/s13293-019-0263-5

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