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Quantitative structure–activity relationship to predict the anti-malarial activity in a set of new imidazolopiperazines based on artificial neural networks

BACKGROUND: After years of efforts on the control of malaria, it remains as a most deadly infectious disease. A major problem for the available anti-malarial drugs is the occurrence of drug resistance in Plasmodium. Developing of new compounds or modification of existing anti-malarial drugs is an ef...

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Detalles Bibliográficos
Autores principales: Yousefinejad, Saeed, Mahboubifar, Marjan, Eskandari, Rayhaneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744662/
https://www.ncbi.nlm.nih.gov/pubmed/31521174
http://dx.doi.org/10.1186/s12936-019-2941-5