Lentivirus-mediated CDglyTK gene-modified free flaps by intra-artery perfusion show targeted therapeutic efficacy in rat model of breast cancer

BACKGROUND: Free flap-mediated gene therapy in the tumor bed following surgical resection is a promising approach in cancer targeted treatment of residual disease. We investigated the selective killing efficacy of a lentivirus-mediated cytosine deaminase-thymidine kinase (CDglyTK) gene in transplant...

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Detalles Bibliográficos
Autores principales: Zhang, Jianhua, Liu, Yuanbo, Zang, Mengqing, Zhu, Shan, Chen, Bo, Li, Shanshan, Xue, Bingjian, Yan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744674/
https://www.ncbi.nlm.nih.gov/pubmed/31521130
http://dx.doi.org/10.1186/s12885-019-6111-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744674/
https://www.ncbi.nlm.nih.gov/pubmed/31521130
http://dx.doi.org/10.1186/s12885-019-6111-5

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