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PRSS1 mutation: a possible pathomechanism of pancreatic carcinogenesis and pancreatic cancer
BACKGROUND: Previous studies revealed somatic mutations of the cationic trypsinogen gene (PRSS1) in patients with chronic pancreatitis and pancreatic cancer. However, whether PRSS1 mutations trigger pancreatic cancer and/or promote malignant proliferation and metastasis in pancreatic cancer remains...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744682/ https://www.ncbi.nlm.nih.gov/pubmed/31521106 http://dx.doi.org/10.1186/s10020-019-0111-4 |