PRSS1 mutation: a possible pathomechanism of pancreatic carcinogenesis and pancreatic cancer

BACKGROUND: Previous studies revealed somatic mutations of the cationic trypsinogen gene (PRSS1) in patients with chronic pancreatitis and pancreatic cancer. However, whether PRSS1 mutations trigger pancreatic cancer and/or promote malignant proliferation and metastasis in pancreatic cancer remains...

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Detalles Bibliográficos
Autores principales: Liu, Qicai, Guo, Ling, Zhang, Sheng, Wang, Jingwen, Lin, Xinhua, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744682/
https://www.ncbi.nlm.nih.gov/pubmed/31521106
http://dx.doi.org/10.1186/s10020-019-0111-4

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