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The uric acid crystal receptor Clec12A potentiates type I interferon responses

The detection of microbes and damaged host cells by the innate immune system is essential for host defense against infection and tissue homeostasis. However, how distinct positive and negative regulatory signals from immune receptors are integrated to tailor specific responses in complex scenarios r...

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Detalles Bibliográficos
Autores principales: Li, Kai, Neumann, Konstantin, Duhan, Vikas, Namineni, Sukumar, Hansen, Anne Louise, Wartewig, Tim, Kurgyis, Zsuzsanna, Holm, Christian K., Heikenwalder, Mathias, Lang, Karl S., Ruland, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744871/
https://www.ncbi.nlm.nih.gov/pubmed/31451663
http://dx.doi.org/10.1073/pnas.1821351116