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The uric acid crystal receptor Clec12A potentiates type I interferon responses
The detection of microbes and damaged host cells by the innate immune system is essential for host defense against infection and tissue homeostasis. However, how distinct positive and negative regulatory signals from immune receptors are integrated to tailor specific responses in complex scenarios r...
Autores principales: | Li, Kai, Neumann, Konstantin, Duhan, Vikas, Namineni, Sukumar, Hansen, Anne Louise, Wartewig, Tim, Kurgyis, Zsuzsanna, Holm, Christian K., Heikenwalder, Mathias, Lang, Karl S., Ruland, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744871/ https://www.ncbi.nlm.nih.gov/pubmed/31451663 http://dx.doi.org/10.1073/pnas.1821351116 |
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