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Phenotypical microRNA screen reveals a noncanonical role of CDK2 in regulating neutrophil migration

Neutrophil migration is essential for inflammatory responses to kill pathogens; however, excessive neutrophilic inflammation also leads to tissue injury and adverse effects. To discover novel therapeutic targets that modulate neutrophil migration, we performed a neutrophil-specific microRNA (miRNA)...

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Detalles Bibliográficos
Autores principales: Hsu, Alan Y., Wang, Decheng, Liu, Sheng, Lu, Justice, Syahirah, Ramizah, Bennin, David A., Huttenlocher, Anna, Umulis, David M., Wan, Jun, Deng, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744913/
https://www.ncbi.nlm.nih.gov/pubmed/31451657
http://dx.doi.org/10.1073/pnas.1905221116