Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis

How pathogenic cluster of differentiation 4 (CD4) T cells in rheumatoid arthritis (RA) develop remains poorly understood. We used Nur77—a marker of T cell antigen receptor (TCR) signaling—to identify antigen-activated CD4 T cells in the SKG mouse model of autoimmune arthritis and in patients with RA...

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Detalles Bibliográficos
Autores principales: Ashouri, Judith F., Hsu, Lih-Yun, Yu, Steven, Rychkov, Dmitry, Chen, Yiling, Cheng, Debra A., Sirota, Marina, Hansen, Erik, Lattanza, Lisa, Zikherman, Julie, Weiss, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744919/
https://www.ncbi.nlm.nih.gov/pubmed/31455730
http://dx.doi.org/10.1073/pnas.1904271116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744919/
https://www.ncbi.nlm.nih.gov/pubmed/31455730
http://dx.doi.org/10.1073/pnas.1904271116

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