Inventories of naive and tolerant mouse CD4 T cell repertoires reveal a hierarchy of deleted and diverted T cell receptors

Deletion or T(reg) cell differentiation are alternative fates of autoreactive MHCII-restricted thymocytes. How these different modes of tolerance determine the size and composition of polyclonal cohorts of autoreactive T cells with shared specificity is poorly understood. We addressed how tolerance...

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Detalles Bibliográficos
Autores principales: Hassler, Tobias, Urmann, Emanuel, Teschner, Sebastian, Federle, Christine, Dileepan, Thamotharampillai, Schober, Kilian, Jenkins, Marc K., Busch, Dirk H., Hinterberger, Maria, Klein, Ludger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744931/
https://www.ncbi.nlm.nih.gov/pubmed/31451631
http://dx.doi.org/10.1073/pnas.1907615116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744931/
https://www.ncbi.nlm.nih.gov/pubmed/31451631
http://dx.doi.org/10.1073/pnas.1907615116

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