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Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhancement
Random-pattern skin flaps are commonly used and valuable tools in reconstructive surgery, however, post-operative random skin flap necrosis remains a major and common complication. Previous studies have suggested that activating autophagy, a major pathway for degradation of intracellular waste, may...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745036/ https://www.ncbi.nlm.nih.gov/pubmed/31522191 http://dx.doi.org/10.1038/s41419-019-1704-0 |