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Inhibition of MAPK and STAT3-SOCS3 by Sakuranetin Attenuated Chronic Allergic Airway Inflammation in Mice

Asthma allergic disease is caused by airway chronic inflammation. Some intracellular signaling pathways, such as MAPK and STAT3-SOCS3, are involved in the control of airway inflammation in asthma. The flavonoid sakuranetin demonstrated an anti-inflammatory effect in different asthma models. Our aim...

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Detalles Bibliográficos
Autores principales: Santana, Fernanda P. R., da Silva, Rafael C., Grecco, Simone dos S., Pinheiro, Aruanã J. M. C. R., Caperuto, Luciana C., Arantes-Costa, Fernanda M., Claudio, Samuel R., Yoshizaki, Kelly, Macchione, Mariângela, Ribeiro, Daniel A., Tibério, Iolanda F. L. C., Lima-Neto, Lídio G., Lago, João H. G., Prado, Carla M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745182/
https://www.ncbi.nlm.nih.gov/pubmed/31565031
http://dx.doi.org/10.1155/2019/1356356