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Simultaneous molecular docking of different ligands to His(6)-tagged organophosphorus hydrolase as an effective tool for assessing their effect on the enzyme

BACKGROUND: Enzymatic hydrolysis of N-acyl homoserine lactones (AHLs), which are signaling molecules responsible for the development of antibiotic resistance in gram-negative bacteria, is a potential solution to overcoming antibiotic resistance problem. It has been established that hexahistidine-tag...

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Detalles Bibliográficos
Autores principales: Aslanli, Aysel, Efremenko, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745196/
https://www.ncbi.nlm.nih.gov/pubmed/31565584
http://dx.doi.org/10.7717/peerj.7684