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Simultaneous molecular docking of different ligands to His(6)-tagged organophosphorus hydrolase as an effective tool for assessing their effect on the enzyme
BACKGROUND: Enzymatic hydrolysis of N-acyl homoserine lactones (AHLs), which are signaling molecules responsible for the development of antibiotic resistance in gram-negative bacteria, is a potential solution to overcoming antibiotic resistance problem. It has been established that hexahistidine-tag...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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PeerJ Inc.
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745196/ https://www.ncbi.nlm.nih.gov/pubmed/31565584 http://dx.doi.org/10.7717/peerj.7684 |