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Detection and characterization of estradiol (E2) and unconjugated estriol (uE3) immunoassay interference due to anti-bovine alkaline phosphatase (ALP) antibodies

OBJECTIVES: Competitive immunoenyzmatic assays for estradiol (E2) and unconjugated estriol (uE3) on UniCel DxI 800 Access immunoassay systems (Beckman Coulter) utilize bovine alkaline phosphatase (ALP) for amplification. In these assays, rare ‘IND’ error flags indicate that a relative light unit (RL...

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Detalles Bibliográficos
Autores principales: Maharjan, Anu S., Wyness, Sara P., Ray, Julie A., Willcox, Tanya L., Seiter, Jonathan D., Genzen, Jonathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745434/
https://www.ncbi.nlm.nih.gov/pubmed/31538105
http://dx.doi.org/10.1016/j.plabm.2019.e00131