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Evaluation of IGF1/IGFBP3 Molar Ratio as an Effective Tool for Assessing the Safety of Growth Hormone Therapy in Small-for-gestational-age, Growth Hormone-Deficient and Prader-Willi Children

OBJECTIVE: IGF1 concentration is the most widely used parameter for the monitoring and therapeutic adaptation of recombinant human growth hormone (rGH) treatment. However, more than half the variation of the therapeutic response is accounted for by variability in the serum concentrations of IGF1 and...

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Detalles Bibliográficos
Autores principales: Gaddas, Meriem, Périn, Laurence, Le Bouc, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745465/
https://www.ncbi.nlm.nih.gov/pubmed/30759961
http://dx.doi.org/10.4274/jcrpe.galenos.2019.2018.0277