Hyperoxidation of mitochondrial peroxiredoxin limits H(2)O(2)‐induced cell death in yeast

Hydrogen peroxide (H(2)O(2)) plays important roles in cellular signaling, yet nonetheless is toxic at higher concentrations. Surprisingly, the mechanism(s) of cellular H(2)O(2) toxicity remain poorly understood. Here, we reveal an important role for mitochondrial 1‐Cys peroxiredoxin from budding yea...

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Detalles Bibliográficos
Autores principales: Calabrese, Gaetano, Peker, Esra, Amponsah, Prince Saforo, Hoehne, Michaela Nicole, Riemer, Trine, Mai, Marie, Bienert, Gerd Patrick, Deponte, Marcel, Morgan, Bruce, Riemer, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745495/
https://www.ncbi.nlm.nih.gov/pubmed/31389622
http://dx.doi.org/10.15252/embj.2019101552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745495/
https://www.ncbi.nlm.nih.gov/pubmed/31389622
http://dx.doi.org/10.15252/embj.2019101552

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